A topical peptide serum clinically proven to visibly minimize expression wrinkles and dynamic lines — without injections. P-TIOX is SkinCeuticals' answer to topical wrinkle relaxation, built on a six-peptide complex with niacinamide that targets the appearance of repetitive motion lines on the forehead, between the brows, and around the eyes.
The peptide complex works by helping calm the appearance of muscle-driven expression lines, while niacinamide supports overall skin tone and texture. The result is smoother, softer-looking skin in the areas most prone to dynamic wrinkling — particularly for clients who want topical support between or instead of injectables.
Why we carry it
This is the serum we recommend to clients who don't want Botox, can't get it, or want to extend the smoothness between appointments. Not everyone is interested in injectables — and not everyone is a candidate — but most people still want softer expression lines. P-TIOX is the closest topical answer SkinCeuticals has put out, and we've seen visible results on clients who use it consistently. It pairs especially well with BOOST lifts and microneedling for compound results: lift the brow, smooth the surface, soften the lines. Use it morning and night, layered under moisturizer, and give it the full clinical window — peptides need time to perform.
Key actives
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Six-peptide complex — clinically formulated to visibly soften the appearance of expression lines and dynamic wrinkles.
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Niacinamide — supports tone evenness and surface smoothness.
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Lightweight serum texture — absorbs cleanly and layers under any moisturizer or SPF.
How to use
- After cleansing and antioxidant serum, apply 4 drops to clean, dry skin in the AM and PM.
- Press into forehead, between the brows, around the eyes, and anywhere expression lines are visible.
- Follow with moisturizer and, in the AM, broad-spectrum SPF.
Best for
Clients who don't want or can't get Botox, anyone wanting to extend results between injectable appointments, and skin with visible expression lines on the forehead, glabella, or around the eyes. Pairs well with BOOST lifts and microneedling for layered, non-injectable smoothing.
Size: 30 ml
