The most powerful brightening serum in the iS Clinical line. Super Serum Advance+ combines 15% L-Ascorbic Acid, Bioidentical Copper Tripeptide-1, hyaluronic acid, and a botanical brightening blend to fade pigmentation, even tone, soften scarring, and visibly firm — all in one bottle.
Copper Tripeptide is the standout active here: it's one of the few peptides with strong clinical support for wound healing, hyperpigmentation, and the appearance of scar tissue. Pair it with high-potency vitamin C and skin gets brighter, smoother, and more even in a matter of weeks.
Why we carry it
This is the bottle we recommend to clients with melasma, post-acne hyperpigmentation, stretch marks they want softened, or surgical and acne scars they're trying to fade. It also stacks beautifully into our ProCell and microneedling protocols — copper peptides plus controlled wound healing is a textbook combination for scar revision. We send this home with PMU clients to fade old, oxidized brow pigment and with anyone who's done a TCA or aggressive resurfacing peel.
Key actives
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L-Ascorbic Acid 15% — high-potency Vitamin C for brightness and collagen.
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Copper Tripeptide-1 — supports wound healing, scar revision, and the look of firmness.
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Hyaluronic Acid — hydration that cushions actives and prevents irritation.
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Kojic Acid + Mushroom Extract — safely brighten uneven tone.
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Botanical Antioxidants — broad-spectrum free radical defense.
How to use
- After cleansing, apply 2–3 drops to face, neck, and any area with scarring or pigment.
- Follow with moisturizer. Always SPF in the AM.
- Use AM and PM for max results. Layer beneath Retinol+ for advanced users.
Best for
Melasma, post-acne hyperpigmentation, scar tissue, stretch marks, mature or sun-damaged skin. Anyone wanting clinical-grade brightening without prescription tretinoin.
Size: 15 ml