iS Clinical Super Serum Advance+

The most powerful brightening serum in the iS Clinical line. Super Serum Advance+ combines 15% L-Ascorbic Acid, Bioidentical Copper Tripeptide-1, hyaluronic acid, and a botanical brightening blend to fade pigmentation, even tone, soften scarring, and visibly firm — all in one bottle.

Copper Tripeptide is the standout active here: it's one of the few peptides with strong clinical support for wound healing, hyperpigmentation, and the appearance of scar tissue. Pair it with high-potency vitamin C and skin gets brighter, smoother, and more even in a matter of weeks.

Why we carry it

This is the bottle we recommend to clients with melasma, post-acne hyperpigmentation, stretch marks they want softened, or surgical and acne scars they're trying to fade. It also stacks beautifully into our ProCell and microneedling protocols — copper peptides plus controlled wound healing is a textbook combination for scar revision. We send this home with PMU clients to fade old, oxidized brow pigment and with anyone who's done a TCA or aggressive resurfacing peel.

Key actives

• L-Ascorbic Acid 15% — high-potency Vitamin C for brightness and collagen.
• Copper Tripeptide-1 — supports wound healing, scar revision, and the look of firmness.
• Hyaluronic Acid — hydration that cushions actives and prevents irritation.
• Kojic Acid + Mushroom Extract — safely brighten uneven tone.
• Botanical Antioxidants — broad-spectrum free radical defense.

How to use

1. After cleansing, apply 2–3 drops to face, neck, and any area with scarring or pigment.
2. Follow with moisturizer. Always SPF in the AM.
3. Use AM and PM for max results. Layer beneath Retinol+ for advanced users.

Best for

Melasma, post-acne hyperpigmentation, scar tissue, stretch marks, mature or sun-damaged skin. Anyone wanting clinical-grade brightening without prescription tretinoin.

Size: 15 ml